September 3, 2018 7:00 PM / Everyone

Space and time in entorhinal-hippocampal systems

Nobel Prize winner Prof. Dr. Edvard Moser becomes honorary member of FIAS

Edvard Moser
Edvard Moser

Venue: FIAS Hörsaal

On September 3, a ceremony will take place to mark the appointment of Nobel Prize winner Prof. Dr. Edvard Moser as FIAS Senior Fellow Laureatus. This award is donated by the STIFTUNG GIERSCH.

After the award ceremony, Prof. Moser will give a lecture in English entitled "Space and time in entorhinal-hippocampal systems".

Abstract:

The ability to map space is critical to survival. In mammals, space is mapped by neural networks in the hippocampus and the entorhinal cortex. These brain areas contain specialized position-coding cell types, including grid cells, which are active only when animals are at locations that tile environments in a periodic hexagonal pattern. I will first show how space is mapped by spatial cells in the medial entorhinal cortex. I will show that grid cells and other medial entorhinal cells form a low-dimensional representation whose structure persists across behavioural tasks and activity states. This representation includes a new type of cell – object-vector cells – which represent position as vectors from prominent landmarks in the arena space. Then I will switch to time, which is less well understood. I will show how episodic temporal information is encoded across scales from seconds to hours within the overall population state of the lateral entorhinal cortex. In the hippocampus, this task-dependent representation of time may be integrated with spatial inputs from medial entorhinal cortex, allowing it to store a unified representation of experience.

Afterwards we invite you to a reception at the Faculty Club on the 4th floor.

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